Brand from Japan: THE RETINOTIME. The active ingredient niacinamide, proven to improve wrinkles, targets both the epidermis and dermis, improving wrinkles on the hands.Long-lasting, highly moisturizing.With each application, pure retinol* penetrates to the stratum corneum, leaving hands plump and firm. *Retinol oil solution (Vitamin A 166, 6671 U/g).Improves wrinkles. Suppresses melanin production and prevents blemishes and freckles. Conditions the skin. Keeps skin healthy. Moisturizes the skin. Protects the skin. Prevents skin dryness.How to use:Take an appropriate amount and gently rub it into your hands until the capsules burst.